Horton

Glycosidic thiol groups can be introduced into glycosyl bromides by successive reactions with thiourea and aqueous sodium disulfite (D. Horton, 1963 M. Cemy, 1961, 1963). Such thiols are excellent nucleophiles in weakly basic media and add to electrophilic double bonds, e.g., of maleic esters, to give Michael adducts in high yields. Several chiral amphiphiles have thus been prepared without any need for chromatography (J.-H. Fuhrhop, 1986 A). 

Pandey, S. McHale, M. E. R. Horton, A. M. et al. Kinetics-Based Indirect Spectrophotometric Method for the Simultaneous Determination of Mn04 and Gt207 ,... 

E. W. Horton, ia S. M. Roberts and F. Sclieinmann, eds.. Chemist, biochemistry, and PharmacologicalMctivity of Prostanoids, Pergamon Press, Oxford,... 

E. W. Horton, Prostaglandins Monographs on Fndocrinology, Spriager-Vedag, Berlin, 1972, p. 141. 

Horton ThermaprillProcess, Bull. No. 8305P, HPD Incorporated, Naperville, hi., 1978. 

C.-H. Wong and co-workers iu D. Horton, L. D. Hawkius, G. J. McGarvey, eds.. Trends in Synthetic Carbohydrate Chemistry, ACS Symposium Series,... 

Chromium ammonium sulfate (I2H2O) [34275-72-4 (hydr) I3548-43-I (anhydr)] M 478.4, m 94 loses 9H2O then dehydr at 300 , d 1.72. Crystd from a saturated aqueous soln at 55° by cooling slowly with rapid mechanical stirring. The resulting fine crystals were filtered on a Buchner funnel, partly dried on a porous plate, then equilibrated for several months in a vacuum desiccator over crude chromium ammonium sulfate (partially dehydrated by heating at 100° for several hours before use) [Johnson, Hu and Horton J Am Chem Soc 75 3922 1953]. 

Use Horton and Franklin s relationship for tower balance in mols/hr. This is shown in Table 1. 

---