Hormonal Terbutaline

Pseudoephedrine dosed at 30 to 60 mg/day taken at bedtime has been used to prevent or decrease the number of episodes of priapism.6 Terbutaline 5 mg has been used orally to prevent priapism with mixed results.38,39 Leuprolide, a gonadotropinreleasing hormone, also has been used for this indication. Hydroxyurea may be helpful in some patients. The use of antiandrogens is under investigation.6,27... 

Indirect response models have been successfully applied for a number of drugs that display a relatively slow onset of effect compared to their distribution to the site of action. Examples are corticosteroids, warfarin, furosemide and terbutalin. Such models are also particularly appropriate if the measured response is a change in circulating blood cells or endogenous proteins (e.g. hormones or cytokines). 

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