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Hopkins and Groom

In 2002, Hopkins and Groom published a study in which they estimated the number... [Pg.349]

Hopkins, A.L. and Groom, C.R. (2002) The druggable genome. Nature Reviews Drug discovery, 1, 727-730. [Pg.51]

Sperandio, O., Reynes, C.H., Camproux, A.C., and Vdloutreix, B.O. (2009) Rationalizing the chemical space of protein—protein interaction inhibitors. Drug Discovery Today, 15 (5-6), 220-229. Hopkins, A.L. and Groom, C.R. (2002) The druggable genome. Nature Reviews. Drug Discovery, 1, 727-730. [Pg.458]

Hopkins, A. L., Groom, C. R., and Alex, A. (2004). Ligand efficiency A useful metric for lead selection. Drug Disc. Today 9 430-431. [Pg.172]

A.L. Hopkins, C.R. Groom, and A. Alex, Ligand efficiency a useful metric for lead selection, Drug Discov. Today, 9, 430-431 (2004). [Pg.59]

FIGURE 25.3 Physicochemical property distributions of proximately 75,000 biologically active Ugands found in Pfizer s screening data as a function of target type. Source Data courtesy of Barker, Snarey, Groom and Hopkins. [Pg.528]

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