Homopolymers Sequencing

Diblock copolymers, as illustrated in Fig. 5.8 c), comprise homopolymer sequences of the two monomers linked together. The homopolymer blocks may be either compatible or incompatible, depending on their chemical structure. If the sequences are compatible, they will mix to form a material with characteristics similar to those of a blend of the two homopolymers. On the other hand, if the blocks are incompatible, they will tend to segregate from one another to form distinct phases. Each phase will display properties characteristic of the homopolymer, modified by the constraints placed on them by having one end attached... 

In distinct contrast to the types of copolymer described earlier, block and graft copolymers usually show properties characteristic of each of the constituent homopolymers. They also have some unique properties arising from the chemical linkage(s) between the homopolymer sequences preventing them from acting entirely independently of each other. 

A copolymer sample produced by reactive blending of two homopolymers is made of three components the two homopolymers and the copolymer formed. As the reaction goes on, the two homopolymer sequences disappear and the copolymer sequences become abundant. 

The conformational differences along a DNA molecule caused by the presence of homopolymer sequences in DNA (Kates, 1971) might also cause preferential shearing of the DNA in these regions. Homopolymer sequences are by definition the most repetitious of all nucleotide sequences, and they would therefore be likely to participate in the formation of circular DNA molecules in vitro. 

Sequential Thiol-Epoxy and Esterification Reactions A Facile Route to Bifunctional Homopolymer Sequences... 

Fig. 1 Cartoon representation of a bifunctionalized random copolymer (/e/t), and a homopolymer sequence in which each polymer repeat unit carries a 1 1 ratio of the active residues (right)...

Scheme 5 Second functionalization of the mono-functionalized homopolymer sequence...

Stuparu MC, Khan A (2014) Sequential thiol-epoxy and esterification reactions a facile route to bifunctional homopolymer sequences. Adv Polym Sci. doi 10.1007/12 2014 299... 

Copolymers are macromolecules composed of two or more chemically distinct monomer units, covalently joined to form a common polymer chain [1,2], In these materials, the sequence distribution of the monomer counits plays a critical role in determining the copolymer s crystallization behavior, and consequently influences its solid-state morphology and material properties [1,2], At one extreme, different types of monomer units may be randomly incorporated into the polymer chain, resulting in a statistical copolymer. At the other extreme, blocks of homopolymer sequences of different chemical nature and chain length may be joined together to form what is known as a block copolymer. In this chapter, we wiU review the key effects of comonomer incorporation on the solid-state morphology and crystallization kinetics in both statistical and block copolymers. 

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