Chemokine homeostatic

Trentin, L., Cabrelle, A., et al. (2004). Homeostatic chemokines drive migration of malignant B cells in patients with non-Hodgkin lymphomas. Blood 104(2) 502-8. Epub 2004 Mar 4. 

Inflanunatory chemokines have also been described as inducible chemokines, whereas homeostatic chemokines are also known as lymphoid or constitutive chemokines. 

Until recently, the structural subclassification based on the arrangement of the cysteine motif was an adequate classification system for chemokines and their receptors. However, this classification based on structure did not provide any indication of the functional role of the various chemokines. Therefore, an alternative system that relates expression to function has recently been developed. In this system, chemokines and chemokine receptors are classified according to their functional expression as either homeostatic/constitutive or inflamma-tory/inducible (Fig. 2). Homeostatic chemokines are expressed constitutively within lymphoid tissues and regulate movement of thymocytes through the thymus during selection and... 

Anders, H. J., Romagnani, P., Mantovani, A. (2014). Pathomechanisms Homeostatic chemokines in health, tissue regeneration, and progressive diseases. Trends in Molecular Medicine, 20, 154—165. 

Haraldsen, G., Rot, A. (2006). Coy decoy with a new ploy Interceptor controls the levels of homeostatic chemokines. European Journal of Immunology, 36, 1659—1661. 

Zlotnik, A., Burkhardt, A. M., Homey, B. (2011). Homeostatic chemokine receptors and organ-specific metastasis. Nature Reviews. Immunology, 11(9), 597—606. 

Gardner, L, Patterson, A.M., Ashton, BA., Stone, M.A., and Middleton, (. (2004) The htunan Duffy antigen binds selected inffammatory but not homeostatic chemokines. Biochemical and Biophysical Research Communications. 321, 306-312. 

Muller, G. et al. (2002) Systemic immunoregulatory and pathogenic functions of homeostatic chemokine receptors. Journal of Leukocyte Biology, 72, 1-8. 

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