Histamine agonists antagonists

Very recently, a very bold chemical model for histamine H2-receptors has been proposed using [18]aneN6-3H+ 84), which can chemically recognize histamine, histamine H2-agonists, and histamine H2-antagonists such as cimetidine XII or ranitidine XIII that are currently in world-wide use for treatment of peptic ulcers 85). 

Histamine-receptor Antagonists Serotonin agonists Serotonin antagonists Ergot alkaloids... 

Seifert, R., Hoer, A., Schwaner, I., Buschauer, A. (1992). Histamine increases cytosolic Ca2+ in HL-60 promyelocytes predominantly via H2 receptors with an unique agonist/ antagonist profile and induces functional differentiation. Am. Soc. Pharmacol. Exp. Therapeut. 42,235-41. 

Histamine H3 antagonists 5-HT3 receptor agonist 5-HTlA receptor agonist 5-HT6 antagonist Serotonin stimulant FK-960 Fujisawa... 

N.-Y. Shih, Imidazolyl-Alkyl-Piperazine and -Diazepine Derivatives as Histamine H3 Agonists/Antagonists, PCT Int. Patent Appl. WO 93/12093 (1993). 

Arpimycin erythromycin, arprinocid [ban, inn, usan) is an anticoccidial agent. arpromidine [inn) (bu eso he 90371) is a substituted imidazolylguanidine, a (H,) histamine receptor antagonist, but a (Hj) histamine RECEPTOR agonist. 

Functionalized oxadiazoles have received considerable attention in the pharmaceutical industry as heterocyclic amide and ester isosteres [95]. Oxadiazoles have been employed in the design of biologically active templates, e. g. core structures for muscarinic agonists, kinase inhibitors, anti-inflammatory agents, histamine H3 antagonists, monoaminic oxidase inhibitors, etc. 

Ozaki, Y, Kume, S., and Ohashi, T, 1984, Effects of histamine agonists and antagonists on luminol-dependent chemiluminescence of granulocytes. Agents Actions 15 182-188. 

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