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Hippocampus lead vulnerability

Experimental studies on the hippocampus suggest a special vulnerability to lead. Louis-Ferdinand (1978) administered 7.5mg/kg lead acetate via intraperitoneal injection daily from birth to postnatal day 10 and reported a decrease in thickness of the hippocampal cell layer. This deficit was especially evident in the dentate gyrus, in which the granular cell layer showed a lowered neuronal density and prominent nucleoli, and within the hippocampal formation, where the pyramidal cell layer exhibited reduction in thickness. Although this study did not state blood lead values, there was no... [Pg.117]


See other pages where Hippocampus lead vulnerability is mentioned: [Pg.486]    [Pg.634]    [Pg.482]    [Pg.206]    [Pg.300]    [Pg.187]    [Pg.189]    [Pg.96]    [Pg.1802]    [Pg.438]    [Pg.389]    [Pg.132]    [Pg.151]    [Pg.643]    [Pg.37]    [Pg.501]    [Pg.143]    [Pg.625]    [Pg.372]    [Pg.682]   
See also in sourсe #XX -- [ Pg.117 ]




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