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High resolution proteomics technologies

Figure 10.1 The SMART approach is built on drugs with proven in vitro efficacy, common pharmacological in vitro models, and high resolution proteomics technologies. Alternative drug targets are subsequently identified and evaluated for their potential in drug screening programs. Figure 10.1 The SMART approach is built on drugs with proven in vitro efficacy, common pharmacological in vitro models, and high resolution proteomics technologies. Alternative drug targets are subsequently identified and evaluated for their potential in drug screening programs.
Significant improvements in the technologies of high-resolution two-dimensional Polyacrylamide Gel Electrophoresis (2-D PAGE) and Mass Spectrometry (MS) have marked the start of proteome analysis. Proteomics permits the analysis of thousand of proteins simultaneously, and have the potential to identify markers for early detection, classification and prognosis of diseases, as well as pinpointing targets for improved treatment outcomes [42]. [Pg.527]

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Proteomic technologies

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