High-performance liquid chromatography partition coefficients

Lipophilicity represents the affinity of a molecule or a moiety for a lipophilic environment. It is commonly measured by its distribution behavior in a biphasic system, either liquid-liquid (e.g. partition coefficient in 1-octanol-water) or solid-liquid (retention on reversed-phase high-performance liquid chromatography or thin-layer chromatography system). [Pg.35]

Sangster, J. Octanol-Water Partition Coefficients Fundamentals and Physical Chemistry, Wiley, Chichester, 1997. n Valko, K. Application of high-performance liquid chromatography based measurements of lipophilicity to model biological distribution. J. Chromatogr. A 2004, 1037, 299-310. [Pg.350]

Krikorian SE, Chom TA, King JW. 1987. Determination of octanol/water partition coefficients of certain organophosphorus compounds using high-performance liquid chromatography. Quant Struct-Act Relat 6(2) 65-69. [Pg.150]

Fujisawa S, Masuhara E. 1981. Determination of partition coefficients of acrylates, methacrylates, and vinyl monomers using high performance liquid chromatography (HPLC). J Biomed Mater Res 15 787- 793. [Pg.108]

Griffin, S., Grant Willie, S., Markham, J. (1999) Determination of octanol-water partition coefficient for terpenoids using reversed-phase high performance liquid chromatography. J. Chromatog. A, 864, 221-228. [Pg.399]

De Kock, A.C., Lord, D.A. (1987) A simple procedure for determining octanol-water partition coefficients using reversed phase high performance liquid chromatography (RPHPLC). Chemosphere 16(1), 133-142. [Pg.607]

Donovan, S.F., Pescatore, M.C. (2002) Method for measuring the logarithm of the octanol-water partition coefficient by using short octadecyl-poly(vinyl alcohol) high-performance liquid chromatography columns. J. Chromatogr. A, 952, 47-61. [Pg.608]

Miyake, K., Terada, H. (1982) Determination of partition coefficients of very hydrophobic compounds by high performance liquid chromatography on glyceryl-coated controlled-pore glass. J. Chromatogr. 240, 9-20. [Pg.612]

Nahum, A., Horvath, C. (1980) Evaluation of octanol-water partition coefficients by using high-performance liquid chromatography. J. Chromatogr. 192, 315-322. [Pg.612]

Sherblom, P.M., Eganhouse, R.P. (1988) Correlations between octanol-water partition coefficients and reversed-phase high-performance liquid chromatography capacity factors. J. Chromtogr. 454, 37-50. [Pg.614]

Vowles and Mantoura [38] determined sediment-water partition coefficients and the high-performance liquid chromatography capacity factors for 14 alkylbenzene and polyaromatic hydrocarbons. The partition coefficients correlated well with the alkyl-cyano capacity factors, and it was concluded that this phase gave a better indication of sorption on sediment than either the octanol or octadecylsilane phases. [Pg.127]

J.C. Kraak, H.H. van Rooij, and J.L.G. Thus, Reversed-phase ion-pair systems for the prediction of n-octanol/water partition coefficients of basic compounds by high-performance liquid chromatography , J. Chromatogr., 1986, 352,455. [Pg.95]

Nakamura, M., Suzuki, T., Amano, K., and Yamada, S. Relation of sorption behavior of agricultural chemicals in solid-phase extraction with their n-octanolAvater partition coefficients evaluated by high-performance liquid chromatography. Anal Chim. Acta, 428(2) 219-226, 2001. [Pg.1700]

Paschke, A., Neitzel, P.E., Walther, W., and Schiirmann, G. Octanol/water partition coefficient of selected herbicides determination using shake-flask method and reversed-phase high-performance liquid chromatography, J. Chem. Eng. Data, 49(6) 1639-1642, 2004. [Pg.1707]

Mirrlees, M., S. Moulton, C. Murphy, and P. Taylor. 1976. Direct Measurement of Octanol/Water Partition Coefficients by High Performance Liquid Chromatography. J. Med. Chem. 19, 615-626. [Pg.133]