High-performance anion-exchange electrochemical detection

Lin, S. L., Inoue, Y., and Inoue S., Evaluation of high-performance anion-exchange chromatography with pulsed electrochemical and fluorometric detection for extensive application to the analysis of homologous series of oligo-and polysialic acids in bioactive molecules, Glycobiology, 9, 807, 1999. 

Corradini, C., Cavazza, A. and Bignardi, C. (2012) High-performance anion-exchange chromatography coupled with pulsed electrochemical detection as a powerful tool to evaluate carbohydrates of food interest principles and applications, Int. J. Carbohydr. Chem., doi 10.1155/2012/487564. 

GC, for their direct detection of carbohydrates, with high sensitivity and specificity and without the need for sample derivatization. Specifically, the technique of high-performance anion-exchange chromatography with pulsed electrochemical detection (HPAEC-PED) is fast becoming the technique of choice for this. HPLC techniques with R1 detection are greatly limited in their ability to analyze complex carbohydrates in foods. 

In a non-electrochemical method with N4 type complexes, Kimura et al. [50] detected volatile organic compounds using a Quartz Crystal Microbalance coated with SAM s of nanostructured macromolecular metal complexes of Co-Pc, Ni-Pc, Cu-Pc or Zn-Pc in the form of polymer brushes. The method was based on the highly hydrophilic character of the brushes and on their good performance as anion exchangers... 

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