Hexahydro azocine

Reductions. Dehydrogenation of azocane 275 was performed in the presence of CaC03 and produced hexahydro-azocine 276 (Scheme 115 <1998JA3613>). 

Azocin-2( 1H )-one, hexahydro- 1-phenyl-photochemical rearrangement, 7, 656 Azodn-2( 1H )-one, 1,2,7,8-tetrahydro-synthesis, 7, 662 Azocin-5-one IR spectra, 7, 16 transannular interactions, 7, 14 Azocin-5-one, l-(2,4-dimethylphenyl)-IR spectrum, 7, 657 Azocin-5-one, methoxycarbonyl-synthesis, 7, 657 Azocin-5-one, 1-methyl-IR spectrum, 7, 657 synthesis, 7, 657 Azodn-5-one, 1-p-tolyl-IR spectrum, 7, 657 Azocinones... 

Some other ring expansions involving the intramolecular amino Claisen rearrangement of vinylarylaziridine [ 123], the Diels-Alder reaction of indoles with acetylene derivative [124-127] and the dibromocarbene insertion into quinoline enol ethers [ 128] have been used to prepare 1-benzazepines. On the other hand, treatment of 3-chloro-3-phenyl-l,2,3,4,5,6-hexahydro-l-benz-azocin-2-ones with piperidine causes a ring contraction to give 2-phenyl-2-(l-piperidinylcarbonyl)-2,3,4,5-tetrahydro-l//-l-bcnzazepines in an excellent yield [23]. 

Isomeric hexahydro[l,3]thiazolo[4,5-fc]azocine 208 is formed in the reaction between 3-bromo-2-oxoazocane 207 and thioamide in ethanol (96CPB2070 Scheme 58). 

Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[c/]azocin-8-ol, (2a,6a,11R )-1,2,3,4,5,6-hexahydro-6,11 -dimethyl-3-(3-mmethyl-2-butenyl)-2,6-methano-3-benzazocin-8-ol, C19H27NO, Mr 285.42, mp 145-148 °C hydrochloride [2276-52-0], C19H27NO. ... 

RINGS WITH ONE NITROGEN ATOM 5.19.2.1 Hexahydro- and Octahydro-azocines... 

The reaction of the benzylidene derivative of 5-methyl-6-thioxo-5,6,ll,12-tetrahydrodibenzo[fe,/]azocin-12-one (63) with hydroxylamine has been found to initiate a novel rearrangement to yield the hydroximinoisothiochromene (64), while the mechanism shown in Scheme 24 has been invoked " to explain the formation of 2,3,4,4a-tetrahydropyrrolo[2,l-fc]quinazolin-9(l//)-one-l-carboxylic acids from the treatment of 1,10,11,11 a-tetrahydropyrrolo [2,1 -c] [ 1,4]benzodiazepin-5,11 -diones (65) with concentrated hydrochloric acid. De Lucca has discovered that hexahydro-... 

Azocin-2(l H)-one, 3-bromohexahydro-substitution reactions, 7, 656 Azocin-2( 1H)-one, 3-chlorohexahydro-substitution reactions, 7, 656 Azocin-2(lH)-one, hexahydro-synthesis, 7, 654... 

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