Heterothalamus alienus

Examples of other antimicrobial flavanones isolated from medicinal plants also included (2/ ,3 )-3-acetoxy-5,7,4 -trihydroxyflavanone isolated from Heterothalamus alienus (Spreng.) O. Kze. (Asteraceae), which showed very good activity against standardized as well as chnical isolates of Trichophyton rubrum and Trichophyton mentagrophytes, demonstrating not only fungistatic but also fungicidal properties. ... 

Pacciaroni AV, Gette ML, Derita M, Ariza-Espinar L, Gil RR, Zacchino SA, Silva GL. (2008) Antifungal activity of Heterothalamus alienus metabolites. 

An evaluation of antiviral properties of various EOs from South American plants was carried out by Duschatzky et al. (2005). The authors assessed the cytotoxicity and in vitro inhibitory activity of the EOs against HSV-1, DENV-2, and JUNV by a virucidal test. The best results were observed with the EOs of Heterothalamus alienus (Asteraceae) and Buddleja cordobensis (Scrophulariaceae) against JUNV, with virucidal concentration 50% (VC50) values of 44.2 and 39.0 ppm and therapeutic indices (cytotoxicity to virucidal action ratio) of 3.3 and 4.0, respectively. The oils caused the inhibitory effect interacting directly with the virions. 

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