Heteronuclear single-quantum multiple bond correlation

More recently, a gradient-enhanced heteronuclear single quantum multiple bond correlation (HSQMBC) experiment and its variants34,47,60-62 have been proposed for the measurement of heteronuclear coupling... [Pg.200]

Now a simple, general and pratical method is available for direct measurement of V(ch) coupling constants [73]. ID and 2D heteronuclear single quantum multiple bond correlation (HSQMBC) experiments are easily performed in a routine manner. These experiments are based on the evolution of heteronuclear single quantum coherence (SQC) in... [Pg.1045]

HSQMBC = Heteronuclear Single Quantum Multiple Bond Correlation... [Pg.1067]

HC HMQC (heteronuclear multiple quantum coherence) and HC HSQC (heteronuclear single quantum coherence) are the acronyms of the pulse sequences used for inverse carbon-proton shift correlations. These sensitive inverse experiments detect one-bond carbon-proton connectivities within some minutes instead of some hours as required for CH COSY as demonstrated by an HC HSQC experiment with a-pinene in Fig. 2.15. [Pg.36]

Other strategies that show great promise in reducing NMR acquisition time utilise methods to obtain multiple sets of data from one experiment through a concept known as time-shared evolution. An example of this process that should find utility in natural products elucidation was demonstrated by a pulse sequence called CN-HMBC.93 Traditionally, a separate 13C-HMBC and 15N-HMBC were acquired independently. However, the CN-HMBC allows both 13C- and 15N-HMBC spectra to be obtained simultaneously. By acquiring both data sets simultaneously, an effective 50% time reduction can be achieved.93 This approach has also been demonstrated for a sensitivity-enhanced 2D HSQC-TOCSY (heteronuclear multiple bond correlation total correlation spectroscopy) and HSQMBC (heteronuclear single quantum... [Pg.288]

Fourier transform or transformation heteronuclear chemical-shift correlation heteronuclear multiple bond correlation heteronuclear multiple quantum correlation heteronuclear single quantum correlation... [Pg.358]

The assignment of heteronuclei generally requires acquisition of a heteronuclear single quantum coherence (HSQC) experiment and a heteronuclear multiple bond correlation (HMBC) experiment, and these are described in more detail below. [Pg.296]

The main emphasis of current carbohydrate structural analysis is the applicability of modern multi-dimensional NMR for solving the two crucial problems in complex carbohydrate structural analysis, namely, the elucidation of the sequence of glycosyl residues and the solution conformation and dynamics of a carbohydrate (150). Techniques include 2D Total Correlation Spectroscopy (TOCSY), Nuclear Overhauser effect spectroscopy (NOESY), rotational nuclear Overhauser effect spectroscopy (ROES Y),hetero-nuclear single quantum coherence (HSQC), heteronuclear multiple quantum correlation (HMQC), heteronuclear multiple bond correlation (HMBC), and (pseudo) 3D and 4D extensions. [Pg.232]

In the heteronuclear experiment category, the experiments of interest are the heteronuclear multiple quantum correlation (HMQC) experiment, the heteronuclear single quantum correlation (HSQC) experiment, and the heteronuclear multiple bond correlation (HMBC, including the gradient-selected version gHMBC) experiment. Both the HMQC and HSQC produce similar results, but each has its own unique advantages and disadvantages. [Pg.124]

HMBC. Heteronuclear multiple bond correlation. HMQC. Heteronuclear multiple quantum correlation. HSQC. Heteronuclear single quantum correlation. INADEQUATE. Incredible natural abundance double quantum transfer. [Pg.346]

C-H correlation over one bond Heteronuclear multiple quantum coherence (HMQC), heteronuclear single quantum coherence (HSQC)... [Pg.1064]

M. Takasaki, K. Kimura, Y. Nakagawa, N. Sato, B. Bae, K. Miyatake, M. Watanabe, Complete NMR assignment of a stdfonated aromatic block copolymer via heter-onuclear single-quantum correlation, heteronuclear multiple-bond correlation and heteronuclear single-quantum correlation total correlation spectroscopy, Polym. J. 44 (2012) 845-849. [Pg.202]