Heterocyclic compounds naphthyl derivatives

As well as phenyl derivatives, other products have been prepared by hydrolysis of alkoxysilanes such as cyclohexenyl or naphthyl derivatives as well as heterocyclic compounds based on thienyl rings (Table 31, entries 28-33). Few practical applications have been reported for this type of compound, except for the styryl compound T81C6H4-A-CFI = CH2]s, and the fluorinated TslCeFsJs which have been used in polymer blending (Table 31, entries 13 and 28). ... 

The studies have been extended to esters that contain condensed polyaromatics in the phenolic substructure. For instance, 1-naphthyl acetate gives 2- and 4-acetyl-1-naphthols [22, 30, 42], whereas in the case of 2-naphthyl acetate, 1-, 3-, 6-, and (marginally) 8-acetyl-2-naphthols are obtained [27, 49-53]. The reaction also works with heterocyclic compounds, such as furan [54], pyridine [55-57], indole [58-60], or chromane [61] derivatives. 

Diary] and triaryl or naphthyl carbamates exhibit low herbicidal activity. The substitution of the aryl radical for a heterocyclic radical gives heterocyclic alkyl and dialkyl ureas, of which many examples have been prepared in recent years. The herbicidal activity of urea derivatives containing a heterocyclic radical, such as benzthiazole, thiazole, thiadiazole, oxadiazole and pyridine, is favourable if one or two methyl groups are substituted at the N -nitrogen. The carrier of total or selective action in these derivatives is presumably the heterocyclic part of the molecule. More recently several new groups of compounds have become known, mainly in the patent literature, for which the structure-activity on relationships are still to be elucidated. 

Heating aryl azides in a mixture of a carboxylic acid and polyphosphoric acid affords a useful, fairly general method of fusing an oxazole ring to aromatics and heterocycles.The method suffers from the limitation that bicyclic azides in which the azido substituent is a- to the ring junction give 0-diacetyl derivatives of the 1,4-aminohydroxy compound as, for example, the formation of 98 from a-naphthyl azide ... 

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