Heptyl iodide, reaction

Reactions of formyl complexes with alkylating agents can be more complex than the reductions in Eqs. (15-22). Some examples of simple hydride transfer exist. For instance, (CO)4Fe(CHO) (22) reduces octyl iodide to octane (75%) (27, 28) (C2H5)4N + 25 (Table I) reacts with heptyl iodide (overnight, room temperature, THF) to give heptane (71%) and (CO)4[(ArO)3P]Fe (37, 42) c/.s-(CO)5ReRe(CO)4(CHO) (19) converts octyl iodide to octane (68%) (47). 

The LC-purification of 299 has been simplified by addition of w-heptyl iodide, CH3(CH2)6I, to the post-reaction mixture in order to decrease the amount of the unreacted precursor. 

Ring-protonated alkylcyclopropanes, well-known in solution , were suggested to explain the most unusual behaviour of heptyl ions. Extensive C- and D-labelling as well as a computer simulation and the analysis of CA data indicate that the major fragmentation reactions of CvHj s ions, generated via loss of I from 1-heptyl iodide, are preceded by extensive skeletal reorganization which via cyclopropane-like structures (140, 142, 144) eventually isomerize to tertiary carbocations (145 and 146, Scheme 23 where only the carbon skeleton is shown). The latter serve as actual precursors for the loss of CsH. ... 

The halogen-metal exchange reaction can also be undesirable at times. One illustration, selected from a number, is the attempted coupling between pentafluorophenyllithium and periluorinated heptyl iodide, from which there is obtained an excellent yield of pentafluoroiodobenzene, with no significant coupling. 

Gowenlock and co-workers have shown that the n-heptyl bromide/ sodium reaction leads to cyclohexane [115] whereas the perfluoroheptyl iodide/sodium system does not lead to perfluorocyclohexane [116]. 

Methyl iodide has been used as a mercaptan-blocking group in studies on keratin fibers [87]. Other monofunctional alkyl halides, including benzyl chloride, heptyl bromide, and dodecyl bromide, have also been reacted with reduced keratin fibers [8]. Hall and Wolfram [88] have used this reaction... 

The most often used method is to start with a functional group in a defined position that is easily lost upon ionization. Halogen atoms are mostly used for the production of heptyl ions, the iodides are particularly useful since the intensity of the molecular ion is weak, the heptyl parent ion is relatively abundant and the ions with iodine or fragments thereof contribute to less than 1% of the total ion current They can be considered a clean source of heptyl (or any alkyl) ions. Another possibility are ion/molecule reactions occurring in chemical ionization, either by adding a proton to an olefin, by hydride (or another anion) abstraction with, e.g., Et, or by proton transfer, e.g., by to an... 

A kinetic study of the reactions of s-amyl iodide, j-amyl iodide, and n-heptyl chloride has been carried out in various aqueous ethanol solutions in the presence and absence of OH . For all three substrates, and E2 processes only are found when OH... 

Acyl cyanides are versatile synthetic intermediates and are generally prepared by the reaction of acid chlorides, acid bromides, and occasionally acid anhydrides with metal cyanides. It has now been found that the very reactive acyl iodides, used either preformed or generated in situ, are useful substrates for the preparation of ap-unsaturated and other acyl cyanides. Aryl acyl cyanides are obtained from the flash vacuum pyrolysis of 3-azido-l,2,4-oxadiazoles, and ethoxalyl cyanide from the reaction of di-n-heptyl sulphide with 2,3-dicyano-oxiran-2,3-dicarboxylate. The chemistry of acyl cyanides has been reviewed. ... 

Preparation by reaction of heptyl bromide with 5-allyl-2,4-dihydroxyacetophenone in the presence of potassium carbonate and potassium iodide in refluxing methyl ethyl ketone (77%) [2671], (40%) [2678,2679]. 

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