Hemoglobin Models

Tsuchida, E., and Nishide, H. Hemoglobin Model — Artificial Oxygen Carrier Composed of Porphinatoiron Complexes. 132, 63-99 (1986). 

Table 3.4 lists values for A Eq and for some important oxidation and spin states found in bioinorganic molecules. Data are taken from reference 24 and from Table 1 of reference 25 for hemoglobin, myoglobin, and the picket-fence porphyrin model compound, FeTpivPP(l-Melm).25 The myoglobin and hemoglobin model compounds are discussed in Section 4.8.2. Reference 26 provides the Table 3.4 data on iron sulfur clusters found in many bioinorganic species.26 The unusual iron-sulfur and iron-molybdenum-sulfur clusters found in the enzyme nitrogenase are discussed more fully below and in Chapter 6. 

Early in the search for myoglobin or hemoglobin model compounds for study, it was learned that cobaltoheme substituted into apo—myoglobin or -hemoglobin... 

All successful myoglobin and hemoglobin model compounds provide steric bulk on the distal side of the porphyrin ring with a hydrophobic pocket for complexation of dioxygen as well as a bulky alkyl imidazole proximal ligand... 

VI. H NMR Investigations of Structures and Properties of Symmetric Valency Hybrid Hemoglobins Models for Doubly... 

Symmetric Valency Hybrid Hemoglobins Models for Doubly... 

Hemoglobin Model — Artificial Oxygen Carrier Composed of Porphinatoiron Complexes... 

As a hemoglobin model, using imidazole attached polystyrene) with the picket fence porphyrin-Co(H) (XIV) the reversible oxygen adsorption-desorption reaction is observed (148,149). 

See also Oxygen Binding by Myoglobin, Oxygen Binding by Hemoglobin, Models of Allosteric Activity, Histidine... 

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