Hemoglobin Adair binding model

Linked-function mechanisms for cooperative binding interaction of metabolites and/or drugs, based on the presence of two or more different conformational states of the protein or receptor. See Adair Equation Cooperative Ligand Binding Hemoglobin Hill Equation Plot Koshland-Nemethy-Filmer Model Monod-Wyman-Changeux Model Negative Cooperativity Positive Cooperativity... [Pg.48]

ADAIR EQUATION COOPERATIVE LIGAND BINDING HILL EQUATION PLOT KOSHLAND-NEMETHY-EILMER MODEL MONOD-WYMAN-CHANCEUX MODEL NEGATIVE COOPERATIVITY POSITIVE COOPERATIVITY HEMOGLOBIN ALLOTOPIC EFFECT Allowed electronic transitions,... [Pg.722]

The O2 binding properties of hemoglobin have been mainly represented by two methods as shown in Figure 9. First, the model proposed by Adair and Koshland uses four successive... [Pg.1878]