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Hematopoietic protein tyrosine phosphatase

Sergienko E, Xu J, Liu WH et al (2012) Inhibition of hematopoietic protein tyrosine phosphatase augments and prolong ERKl/2 and p38 activation. ACS Chem Biol 7 367-377... [Pg.24]

Huang Z, Zhou B, Zhang ZY (2004) Molecular determinants of substrate recognition in hematopoietic protein-tyrosine phosphatase. J Biol Chem 279 52150-52159... [Pg.24]

Zanke B, Squire J, Griesser H et al (1994) A hematopoietic protein tyrosine phosphatase (HePTP) gene that is amplified and overexpressed in myeloid malignancies maps to chromosome lq32.1. Leukemia 8 236-244... [Pg.217]

Bobkova EV, Liu WH, Colayco S et al (2011) Inhibition of the hematopoietic protein tyrosine phosphatase by phenoxyacetic acids. ACS Med Chem Lett 2 113—118... [Pg.239]

Cinnamic acid derivatives COOH SPPS (18) COOH Hematopoietic protein tyrosine phosphatase (HePTP) 1C50 = 3.9 /tM... [Pg.131]

A library of cinnamic acid derivatives was prepared on solid phase using a four-component Ugi condensation [429], The results from screening compounds against the hematopoietic protein tyrosine phosphatase (HePTP) indicate that the variations in R2 has a more pronounced effect on potency than do changes in R1. The most potent compound in the series was found for Rl=phenyl and R2=benzyl (library 44 IC50 3.9 //M) [429],... [Pg.132]

Kim CH, Qu CK, Hangoc G, et al. Abnormal chemokine-induced responses of immature and mature hematopoietic cells from motheaten mice implicate the protein tyrosine phosphatase SHP-1 in chemokine responses. J Exp Med 1999 190(5) 681-690. [Pg.284]

Sattler, M., Salgja, R., Shrikhande, G., Verma, S., Choi, J.L., Rohrschneider, L.R., and Griffin, J.D., 1997, The phosphatidyhnositol polyphosphate 5-phosphatase SHIP and the protein tyrosine phosphatase SHP-2 form a complex in hematopoietic cells which can be regulated by BCR/ABL and growth factors. Oncogene, 15 2379-2384. [Pg.332]

Membrane-bound protein tyrosine phosphatase expressed by all hematopoietic cells Appears on all leukocytes promotes intercellular adhesion Cell surface or matrix molecule promotes binding to LFA-1 Intermediate filament protein highly expressed by activated astrocytes Breaks down membrane hpids to form arachidonic acid... [Pg.379]

Lagasse E et al (2000) Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat Med 6 1229-1234 LaMontagne KR Jr et al (1998) Protein tyrosine phosphatase IB antagonizes signalling by oncoprotein tyrosine kinase p210 bcr-abl in vivo. Mol Cell Biol 18 2965-2975 Laneuville P (1995) Abl tyrosine protein kinase. Semin Immunol 7 255-266... [Pg.34]

Saxena M, Williams S, Brockdorff J et al (1999) Inhibition of T cell signaling by mitogen-activated protein kinase-targeted hematopoietic tyrosine phosphatase (HePTP). J Biol Chem 274 11693-11700... [Pg.217]

See other pages where Hematopoietic protein tyrosine phosphatase is mentioned: [Pg.321]    [Pg.85]    [Pg.16]    [Pg.321]    [Pg.85]    [Pg.16]    [Pg.386]    [Pg.770]    [Pg.241]    [Pg.241]    [Pg.723]    [Pg.91]    [Pg.63]   


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