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Hematopoietic protein tyrosine phosphatase HePTP

Zanke B, Squire J, Griesser H et al (1994) A hematopoietic protein tyrosine phosphatase (HePTP) gene that is amplified and overexpressed in myeloid malignancies maps to chromosome lq32.1. Leukemia 8 236-244... [Pg.217]

Cinnamic acid derivatives COOH SPPS (18) COOH Hematopoietic protein tyrosine phosphatase (HePTP) 1C50 = 3.9 /tM... [Pg.131]

A library of cinnamic acid derivatives was prepared on solid phase using a four-component Ugi condensation [429], The results from screening compounds against the hematopoietic protein tyrosine phosphatase (HePTP) indicate that the variations in R2 has a more pronounced effect on potency than do changes in R1. The most potent compound in the series was found for Rl=phenyl and R2=benzyl (library 44 IC50 3.9 //M) [429],... [Pg.132]

Saxena M, Williams S, Brockdorff J et al (1999) Inhibition of T cell signaling by mitogen-activated protein kinase-targeted hematopoietic tyrosine phosphatase (HePTP). J Biol Chem 274 11693-11700... [Pg.217]


See other pages where Hematopoietic protein tyrosine phosphatase HePTP is mentioned: [Pg.321]    [Pg.85]    [Pg.16]    [Pg.321]    [Pg.85]    [Pg.16]    [Pg.241]   
See also in sourсe #XX -- [ Pg.321 ]




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