Hematological neoplasm

There is also no clear association between PCBs and hematopoietic or lymphatic cancers. Investigations of a cohort of Italian capacitor workers found statistically significantly increased mortality from hematological neoplasms in females in the first study (SMR=377, Cl 115-877, p<0.05) (Bertazzi et al. 

Hayes, R. B., Yin, S. N., Dosemeci, M., Li, G. L., Wacholder, S., Travis, L. B., Li, C. Y, Rothman, N., Hoover, R. N., and Linet, M. S. (1997). Benzene and the dose-related incidence of hematologic neoplasms in China. Chinese Academy of Rreventive Medicine—National Cancer Institute Benzene Study Group. J Natl Cancer Inst 1065-1071. 

Bortezomib is FDA-approved for patients with MM who have received 2 prior therapies and are progressing on their current therapy. The drug is being studied in combination with other drugs in MM as well as other hematologic neoplasms and solid tumors. Escalating doses of bortezomib have resulted in dose-limiting GI, hematopoietic, lymphatic, and renal toxicities. 

A family history of blood dyscrasias including hematological neoplasms ... 

Post-transplant malignancies in HSC transplantation patients are seven times more common than primary cancer in the general population. Posttransplant malignancies include solid tumors, hematologic neoplasms, and post-transplantation lymphoproliferative disorder (PTLD) (Libshitz et al. 1978 Worthy et al. 1997). 

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