Hemandia species

Three Hemandia species, namely, H. moerenhoutiana, H. nymphaeifolia (a synonym of H. peltata according to Kubitzki [2]), and H. voyronii, have been used ethnobotanically by inhabitants of Tonga and Madagascar to treat malaria [11,12], postpartum hemorrhage [13], retained placenta [13], and morning sickness [14],... 

Table 1. Summary of Reported Biological Activities of Hemandia Species...

Biological evaluations of isolates from Hemandia species published to date have focused mainly on their cytotoxic, potential cancer chemopreventive, antiplatelet aggregation, and antimalarial activities. Bioactive compounds from the genus Hemandia with their individual activities of these types will be summarized specifically in the following paragraphs. 

The genus Hemandia L. of the family Hemandiaceae is represented by evergreen trees and shrubs [1]. Hemandia consists of approximately 24 species and is widely distributed in pantropical regions [2]. In terms of their economic applications, timbers of some species of Hemandia are used locally for crates, boxes, and cheap plywood [3]. Thus far, six species and one variety have been investigated for their secondary... 

These stmctural types were isolated in the species that occur in Africa (types I, Ib, II, nid, Vni, and X), Asia (aU types, except VIII, X, and XVI), Europe, South America (types I and II), and Central America (types I, Ib, and n) In this family, the bisbenzyhsoquinohnes have the second most numerous (17 alkaloids), the subtypes Ilia, Hie, and Hid are restricted to the genus Gyrocarpus, while HI and Illb occur in Hemandia. In the genus Sparattanthelium only aporphines (I) and benzylisoquinohnes (II) are present, while in the genus Illigera four types were found (I, Ib, II and XVI) (Table I). 

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