Headaches, niacin

Vitamin B3 is a pyridine compound found in fish, meat, liver, cereal husks, nuts, and pulses. Niacin deficiency produces pellagra, which manifests as dermatitis, diarrhea with enteritis, nausea and vomiting, dementia with headache, insomnia, loss of memory, and disturbances of motor and sensory neurons. Anemia and hypoprotcincrnia are common in pellagra chronic alcoholics have more tendency to suffer from pellagra. Com eaters suffer from pellagra because com... 

Niacin or nicotinic acid (Vitamin B5) Meat, liver, cereals, legumes Pellagra. Dermatitis when exposed to sunlight, weakness, insomnia, impaired digestion, diarrhea, dementia, irritability, memory loss, headaches. 

A precursor to the neurotransmitter serotonin, which promotes relaxation and sleep, tryptophan reduces anxiety and helps some forms of depression. It converts to niacin, lowers cholesterol, helps migraine headaches, and stimulates growth hormone. 

Deficiency conditions Thiamine sensory disturbances, retarded growth, fatigue, anorexia Riboflavin visual defects such as blurred vision and photophobia, cheilosis, rash on nose numbness of extremities Niacin or nicotinic acid retarded growth, peiiagra, headache, memory loss, anorexia, insomnia Pyridoxine neuritis, convulsions, dermatitis, anemia, lymphopenia... 

ADP-ribosylation reactions such as DNA repair, calcium mobilization and deacetylation (Kirkland 2009). In addition, at pharmacological concentrations, niacin is an effective agent for the treatment of dislipidemias and atherosclerosis (Prousky et al. 2011). Furthermore, evidence exists that niacin ameliorates acute migraine, chronic tension-type headaches, depression and schizophrenia (Prousky et al. 2011). This chapter focuses on chemical and biochemical aspects of the vitamin. 

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