Haplotypes hypertension

Many SNPs, insertions/ deletions 1891-1892 TC 2138-2139 AA Haplotypes associated with hypertension RGS2 mRNA 1 in fibroblasts and peripheral blood mononuclear cells [125, 134]... [Pg.132]

The intronic 1891 to 1892 TC and 2138 to 2139 AA in/del variants, however, are more common. These variants have been reported to be in linkage disequilibrium and are associated with hypertension in African Americans. Two haplotypes are reported to have significantly different frequencies between hypertensives... [Pg.134]

Riddle EL, Rana BK, Murthy KKet al (2006) Polymorphisms and haplotypes of the regulator of G protein signaling-2 gene in normo-tensives and hypertensives. Hypertension 47 415 20... [Pg.148]

Variants have been of interest because of disease relevance. At least 14 alleles have been reported, yielding foitr different proteins (http //www.cyp-alleles.ki.se). Haplotypes have been considered in the context of essential and thromboembolic preliminary hypertension [1853, 1854], myocardial infarction [1855], left main coronary artery disease [1856], and cardiovascular disease in general [1857],... [Pg.627]

Fu Z, Nakayama T, Sato N, Izumi Y, Kasamaki Y, Shindo A, Ohta M, Soma M, Aoi N, Sato M, Ozawa Y, Ma Y (2008) A haplotype of the CYP4A11 gene associated with essential hypertension in Japanese men. J Hypertens 26 453 61... [Pg.735]

Nakayama T, Soma M, Haketa A, Aoi N, Kosuge K, Sato M, Kanmatsuse K, Kokubun S (2003) Haplotype analysis of the prostaeyelin synthase gene and essential hypertension. Hypertens Res 26 553 557... [Pg.747]

Gu D, Ge D, He J, Li B, Chen J, Liu D, Chen J, Chen R (2004) Haplotypic analyses of the aldosterone synthase gene CYP11B2 associated with stage-2 hypertension in northern Han Chinese. Clin Genet 66 409 16... [Pg.757]

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