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Halogen-containing antibiotics isolation

Rebeccamycin is an antitumor or antibiotic agent isolated from bacteria " and contains a maleimide indolocarbazole framework. The Trp units in this molecule are chlorinated at the C-7 position and a flavin-dependent halogenase was identified as the enzyme that carries out this chlorination (Scheme 10). " There are many other halogenating enzymes known in the literature and these enzymes are responsible for the syntheses of metabolites containing bromine, chlorine, and fluorine. ... [Pg.19]

See other pages where Halogen-containing antibiotics isolation is mentioned: [Pg.346]    [Pg.346]    [Pg.536]    [Pg.309]    [Pg.339]    [Pg.309]    [Pg.339]    [Pg.254]    [Pg.118]   
See also in sourсe #XX -- [ Pg.309 ]

See also in sourсe #XX -- [ Pg.309 ]

See also in sourсe #XX -- [ Pg.29 , Pg.309 ]



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