Hallucinogens definition

Some of the depressant behavioral effects of hallucinogens may involve inhibitory postsynaptic 5-HT receptors. For example, depressant effects of hallucinogens on startle and locomotor activity may result from activation of these receptors, since 5-HT itself has similar effects. Studies on supersensitivity are lacking, however, and, again, the absence of selective antagonists prevents definitive conclusions. 

In summary, however, we do not have a sufficient amount of consistent electrophysiologic data to draw any definitive conclusions concerning the effects of hallucinogenic drugs on either noradrenergic or dopaminergic neurons. 

As part of his investigation of the Psilocybe genus, Guzman noted a common trait among the hallucinogenic species, in addition to the bluing reaction a flour-like smell or taste. Apart from the inherent subjective nature of our sense of smell and taste, a common odor is a trait that definitely does not apply to the European species (also see Chapter 3.2). 

Renowned pharmacologist R. Siegel described hallucinogenic mushroom consumption in California as merely "experimental use". According to his definition, almost all users of psychoactive mushrooms have anywhere from at least one up to 10 experiences, with several weeks or months in between repetitions. Or... 

Definition A drug psychosis, drug dependence, non-dependent drug abuse and accidental poisoning caused by use of opiates, cocaine, stimulants, cannabis or hallucinogens. 

This last criterion is very significant because by definition it excludes the recreational use of stimulants, most depressants, sedatives, inhalants, and hallucinogens. Moderate use of alcohol is possible, and perhaps marijuana (although this seems to be more open to debate). Any recreational use of the other substancesspeed, cocaine, heroin, LSD, solvents, for exampleis probably not possible, given the power of their chemical effects. 

Thai-hallucinogenic at its best-definitely stronger than Colombian Gold. 

Classical hallucinogens are agents that meet the Hollister definition (2) and, in addition, bind at 5-HT2 serotonin receptors and are recognized by DOM-trained animals in tests of stimulus generalization (5). The classical hallucinogens all possess the general structure Ar-C-C-N, where Ar is a substituted phenyl, 3-indolyl, or substituted 3-indolyl moiety C-C is an ethyl or branched ethyl chain and N is a primary, secondary, or tertiary amine. This will be further discussed. (See Chapter 14 for additional information on serotonin receptors.)... 

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