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Haemoglobin polymers

From the above considerations, it appears that chain length is a main characteristic of polymers. Natural macromolecules, particularly in living bodies, can exhibit exact lengths, thus exact molecular masses. For instance haemoglobin molecular mass is known to within one dalton. However, a synthetic polymer... [Pg.15]

H. Sun, H.Y. Ma, and N.F. Hu, Electroactive haemoglobin-surfactant-polymer biomembrane-like films. Bioelectrochem. Bioenerg. 49,1-10 (1999). [Pg.597]

Figure 3.18 Adenosine phosphates in blood on vinyl polymer column. Conditions column, Asahipak GS320 (vinyl alcohol copolymer gel), 50 cm x 7.6 mm i.d. eluent, 0.1 M sodium phosphate buffer containing 3 M sodium chloride pH 7.0 flow rate, 1.0 ml min-, detection, UV 260 nm. Peaks 1, haemoglobin 2, adenosine triphosphate 3, adenosine diphosphate and 4, adenosine monophosphate. Figure 3.18 Adenosine phosphates in blood on vinyl polymer column. Conditions column, Asahipak GS320 (vinyl alcohol copolymer gel), 50 cm x 7.6 mm i.d. eluent, 0.1 M sodium phosphate buffer containing 3 M sodium chloride pH 7.0 flow rate, 1.0 ml min-, detection, UV 260 nm. Peaks 1, haemoglobin 2, adenosine triphosphate 3, adenosine diphosphate and 4, adenosine monophosphate.
Implantation of polymer matrices that contain angiogenic factors requires quantification of the extent of vessel ingrowth. This can either be analysed immunohistochemically or by haemoglobin/red blood cell count in the tissue. These models generally do not allow analysis of the time course of vascularization since this would require the sacrifice of animals. Application in a dorsal skin fold chamber circumvents this experimental problem, as it provides the opportunity to monitor vessel formation at various time points during the experiment. [Pg.241]

Hjerten and co-workers prepared substrate-specific polyacrylamide gels by carrying out cross-linking polymerisation in the presence of proteins [47]. Polymerisation of acrylamide and 7V,A -methylenebisacrylamide was carried out in the presence of cytochrome C and haemoglobin as the templates. After removal of the templates using surfactants and acetic acid, substrate selectivities of the polymer gels were tested by chromatography. The imprinted polymers reportedly showed preferential affinities for their templates. [Pg.287]

In sickle cell disease, haemoglobin S (HbS) when deoxygenated forms polymers which result in the... [Pg.599]


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Haemoglobin

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