Guanosine, molecular structure

Fig. 9. Molecular structures of acyclic nucleosides and guanosine. Different groups (R) are substituted at the N9-position of the guanine moiety...

Applications to cis-Bis(purine)Ft(II) Complexes. There are presently available a large number of cis-bis(N(7)-bound purine base)Ft(II) complexes whose molecular structures have been determined by X-ray diffraction techniques. For the most part, the nucleobase in these systems is a 6-oxopurine derivative (7). Figure 3 presents conformational drawings for three of these complexes the ci -[Pt(en)(1,3,9-trimethyIxanthine)2] " cation (35) the [Pt(en)(guanosine)2] " cation (36) and [Pt(tn)(Me-5 -GMP2)] ... 

On the other hand, the G-quadruplex with a twisted supra molecular architecture represents a nice example of a dynamic chiral supramolecular system, when guanine and guanosine molecules are used. Molecular chirality may be used as a tool to assemble molecules and macromolecules into supramolecular structures with dissymmetric shapes. The supramolecular chirality, which results from both the properties and the way in which the molecular components associate, is by constitution dynamic and therefore examples of large-scale transcription of such virtual chirality remain rare. 

Fig. 13.16. Distribution of the torsion angles 1,4, 7,5, t,. T20, and cfj (in degrees or A, for labeling see Figure 13.15) in adenosine or guanosine fragments, as Wnd in low-molecular-weight crystal structures (left) and in ligands bound to a protein receptor (right)...

Relaxation, CIDNP, and N.Q.R.—Relaxation. Phosphorus-31 and carbon-13 relaxation times are reported for dimethyl methylphosphonate. The mobility of phosphazene polymers has been studied using P spin-lattice relaxation parameters. The structure and mobility of polycrystalline nitrilotrimethylphos-phonic acid was estimated by line shape analysis. Molecular interactions of guanosine monophosphate and ATP have been studied through their relaxation properties. ... 

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