Growth plate chondrocytes

Wang, W., and T. Kirsch, 2002, Retinoic acid stimulates annexin-mediated growth plate chondrocyte... 

Boyan BD, Sylvia VL, Dean DD, Pedrozo H, Del Toro F, Nemere I, Posner GH, and Schwartz Z (1999) 1,25-(0H)2D3 modulates growth plate chondrocytes via membrane receptor-mediated protein kinase C by a mechanism that involves changes in phospholipid metabolism and the action of arachidonic acid and PGE2. Steroids64,129-36. 

The growth plate chondrocytes undergo proliferation, growth, degradation, mineralization, and resorption and provide the support structure for new bone formation. Bones can increase in length and width through this process. Endochondral ossification occurs near the base of the articular cartilage at the joints. 

P14. Postel-Vinay, M. C., Corvol, M. T., Lang, F., Fraud, F., Guyda, H., and Posner, B. 1., Receptors fi>r insulin-like growth fiictors in rabbit articular and growth plate chondrocytes in culture. Exp. Cell Res. 148, 105-116 (1983). 

Houston B, Seawright E, Jefferies D et al (1999) Identification and cloning of a novel phosphatase expressed at high levels in differentiating growth plate chondrocytes. Biochim Biophys Acta 1448 500-506... 

Usdin, T. B., and Fischbach, G. D., 1986, Purification and characterization of a polypeptide from chick brain that promotes the accumulation receptors in chick myotubes, J. Cell Biol. 103 493-507. Wu, L. Y., Sauer, G. R., Genge, B. R., and Wuthier, R. E., 1989, Induction of mineral deposition by primary cultures of chicken growth plate chondrocytes in ascorbate-containing media, J. Biol. Chem. 264 21346-21355. 

Corvol, M.T., Garabedian, M., Du Bois, M.B., et al. 1978. Vitamin D and cartilage. 11. Biological activity of 25-hydroxycholecalciferol and 24,25- and 1,25-dihydroxychole-calciferols on cultured growth plate chondrocytes. Endocrinology 102 1269-74. 

Schwartz, Z., Ehland, H., Sylvia, V.L., et al. 2002. lalpha,25-dihydroxyvitamin D(3) and 24R,25-dihydroxyvitamin D(3) modulate growth plate chondrocyte physiology via protein kinase C-dependent phosphorylation of extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase. Endocrinology 143(7) 2775-86. 

Chintala, S. K., R. R. Miller, and C. A. Mcdevitt. 1995. Role of heparan sulfate in the terminal differentiation of growth plate chondrocytes. Arch Biochem Biophys 316 227-34. 

Olney RC, Wang J, Sylvester JE, Mougey EB. Growth factor regulation of human growth plate chondrocyte proliferation in vitro. Biochem Biophys Res Commun 2004 317(4) 1171-1182. 

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