Grape seed proanthocyanidin extract free radicals

B. Bagchi, M. Bagchi, S.J. Stohs, D.K. Das, S.D. Ray, C.A. Kuszynski, S.S. Joshi and H.G. Pruess, Free radicals and grape seed proanthocyanidin extract importance in human health and disease prevention. Toxicology 148 (2000) 187-197. 

Bagchi, D. et al.. Free radicals and grape seed proanthocyanidin extract importance in human health and disease prevention. Toxicology, 148, 187, 2000. 

Bagchi, D., Oxygen free radical scavenging abilities of vitamins C, E, P-carotene, pycnogenol, grape seed proanthocyanidin extract, astaxanthin and BioAstin in vitro, Final Report to Cyanotech Corporation, Creighton University School of Health Sciences, Omaha, NE, 2001. 

Bagchi D, Garg A, Krohn RL, Bagchi M, Tran MX, Stohs SJ (1997) Oxygen free radical scavenging abilities of vitamins C and E, and A grape seed proanthocyanidin extract in vitro. Res Commun Mol Pathol Pharmacol 95 179-189... 

Bagchi et al. (1997) studied the oxygen free-radical scavenger ability of grape seed proanthocyanidins using a chemiluminescence assay and cytochrome c reduction. The results revealed that on a weight basis (100 mg/L), the grape seed proantho-cyanidin extract was a better inhibitor of both superoxide anion and hydroxyl radical than vitamin C and vitamin E succinate. 

Kalfin, R., Righi, A., Del Rosso, A., Bagchi, D., Gererini, D., Cerinic, M., and Das, D., Activin, a grape seed-derived proanthocyanidin extract, reduces plasma levels of oxidative stress and adhesion molecules (ICAM-1, VCAM-1 and E-selectin) in systemic sclerosis. Free Radical Res., 36, 819,2002. 

---