Gram -negative bacteria biocide sensitivity

As already pointed out, staphylococci and streptococci are generally more sensitive to biocides than are Gram-negative bacteria examples are provided in Table 13.3. On the... 

As already pointed out, staphylococci and streptococci are generally more sensitive to biocides than Gram-negative bacteria examples are provided in Table 18.4. On the other hand, mycobacteria and especially bacterial spores are much more resistant. A major reason for this variation in response is associated with the chemical composition and structure of the outer cell layers such that there is restricted uptake of a biocide. In consequence of this cellular impermeability, a reduced concentration of the antimicrobial compound is available at the target site(s) so that the cell may escape severe injury. Another, less frequently observed, mechanism is the presence of constitutive, biocidedegrading enzymes. 

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