Grafting amino groups onto pendant

Amino acids bearing unsaturated vinyl or allyl groups can be grafted onto pendant hydridosiloxanes by hydrosilylation (14,15). The hydrosilylation reaction involves the addition of Si-H functional compounds to unsaturated organic compounds in the presence of a transition metal catalyst, usually platinum. Several amino acid functionalized siloxanes have been prepared this way first by synthesizing allylcarboxy... 

Santerre and collaborators [72,73] also found that the plasma interaction of polyether urethanes was significantly altered by incorporation of sulfonate groups [73] which could be derivatized with amino adds [72]. The synergistic effect of pendant PEO and sulfonate groups grafted onto polyurethanes resulted in prolonged ex vivo occlusion times [482]. These results corresponded well with... 

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