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Gout Pathogenesis

Levinson DJ, Becker MA. ainical gout and the pathogenesis of hyperuricemia. In Koopman WJ, ed. Arthritis and Allied Conditions, 13th ed. Baltimore, Williams Wilkins, 1997 2041—2071. [Pg.1710]

Agedelo CA, Wise CM. Gout Diagnosis, pathogenesis, and clinical manifestations. Curr Opin Rheumatol 2001 13 234-239. [Pg.1710]

Gutman AB, Yu TE Renal function and gout with a commentary on the renal regulation of urate excretion, and the role of the kidney in the pathogenesis of gout. Am J Med 1957 23 600-622. [Pg.350]

Obviously, the most crucial problem yet to be solved in the pathogenesis of gout is the source and cause of hyperuricemia. Uric acid, the terminal metabolite of the breakdown of endogenous and exogenous purines, is excreted through the kidney. It passes freely through the glomeruli, but is actively reabsorbed in the tubules. Hyperuricemia results either from an over-... [Pg.221]

Studies of the regulation of glutamine metabolism in birds (urecotelic) and mammals (ureotelic) may be relevant to the pathogenesis of gout. The major func-... [Pg.223]

Furthermore, we have considered the effects of alcohol on serum lipids (Darlington and Scott, impublished work) and noted a nonsignificant reduction in lipid and uric acid levels in gout patients after four weeks of confirmed alcohol abstention. This suggested that alcohol was only one aetiological factor in the pathogenesis of hyperlipidaemia. [Pg.130]

In recent years there has been an appreciable expansion of our understanding of secondary hyperuricemia and of certain rare sub-types of gout associated with an excessive production of uric acid. Although the pathogenesis of primary hyperuricemia in most subjects remains obscure, it is clear that many such patients have a diminished renal clearance of uric acid (Wyngaarden and Kelley, 1972). [Pg.382]

PPARa), an orphan nuclear receptor that acts as a transcription factor to induce the expression of enzymes involved in fatty acid oxidation (Devchand et al, 1996). Abnormal LTB4 production has been implicated in the pathogenesis of inflammatory bowel disease, psoriasis, rheumatoid arthritis, and gout. [Pg.2]


See other pages where Gout Pathogenesis is mentioned: [Pg.144]    [Pg.144]    [Pg.443]    [Pg.195]    [Pg.1711]    [Pg.500]    [Pg.504]    [Pg.1435]    [Pg.241]    [Pg.221]    [Pg.221]    [Pg.223]    [Pg.135]    [Pg.201]    [Pg.38]    [Pg.39]    [Pg.136]    [Pg.591]    [Pg.555]    [Pg.214]    [Pg.246]   
See also in sourсe #XX -- [ Pg.221 ]




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