Gorge

An arch dam, on the other hand, relies on its shape to withstand the pressure of the water behind it. The arch curves back upstream and the force exerted by the water is transferred through the dam into the river valley walls and to the river floor. They are normally constructed in deep gorges where the geological foundations are veiy sound. The United States s Hoover Dam is an example of a concrete arch dam. 

Blue Bridge Enterprises, Inc. (1996). The Three Gorges Dam—II The Super Dam Along the Yangtze River. New York Author. 

The anionic subsite (Ttp 84 and Phe 330) lies between the peripheral and acylation sites, halfway down the gorge and accommodates the positively charged quaternary ammonium of the choline moiety. Ttp 84 orients the charged part of the substrate to the active centre. This subsite is involved in a cross-talk mechanism with the peripheral anionic site (PAS) [3]. 

The PAS is located at the rim of the aromatic gorge, on the protein s surface. It spans six AChE residues Tyr 72, Tyr 124, Glu 285 and Tip 286, on one side of the gorge entrance, and Asp 74 and Tyr 341, on its opposite side. Its core is comprised of Tip 286 and Asp 74, which accommodates many distinct ligands. BChE also has a PAS, but its relatively aromatic content and the response upon ligand-binding differ significantly from those of AChE. 

Morys P, Gorges U, Krauss HL (1984) Z Naturforsh, B Anorg Chem, Org Chem 39B 458... 

Ondruschka, B., Schoiz, P., Gorges, R., Klemm, W., Schubert, K., Halbritter, A., Lowe, H., Mikrowdrme-ubertrager im Chemisch-technischen Praktikum, Chem. Ing. Tech. 74,11 (2002) 1577-1582. 

R. Kape, K. Wex, M. Pamiske, E. Gorge, A. Wetzel, and D. Werner, Legume root metabolites and VA-mycorrhiza development. J. Plant Physiol. 141 54 (1992). 

D. Werner, S. Bernard, E. Gorge, A. Jacobi, R. Rape, K. Kosch, M. Pamiske, S. Schenk, P. Schmidt, and W. Streit, Competitiveness and communication for effective inoculation by Rhizohium, Bradyrhizohium and vesicular-arbuscular mycorrhiza fungi. Experientia. 50 884 (1994). 

Curtis GH, Hay RL (1972) Further geological studies and potassium-argon dating at Oludvai Gorge and Ngorongoro Crater. In Calibration of Hominid Evolution. Bishop WW, Miller JA (eds), Scottish Academic Press, Edinburgh... 

She smiled. Did I I had forgotten. It will be good to be in the world again. Sometimes I hate this place so much that its as if I m being smothered. I want to scream, but my gorge rises until I could not. ... 

Because the pi of a protein is based on its amino acid sequence, this technique has good resolving power. The resolution can be adjusted further by changing the range of the pH gradient. The use of immobilized pH gradient (IPG) strips has enabled reproducible micropreparative fractionation of protein samples, which is not consistently possible when ampholytes are used in the first dimension (Gorg et al., 2000). 

Gorg, A., Obermaier, C., Boguth, G., Harder, A., Scheibe, B., Wildgruber, R., and Weiss, W. (2000). The current state of two-dimensional electrophoresis with immobilized pH gradients. Electrophoresis 21, 1037-1053. 

Olduvay Gorge, Tanzania Fleischer et al. (1965a, 1965b, 1965c)... 

Fleischer, R. L., P B. Price, and R. M. Walker (1965c), Fission track dating of Bed I, Olduvay Gorge, Science 148, 72-7A.. 

Chen J, Chen Z, Xu K, Wei T, Li M, Wang Z, Masataka W (2005) ADP- flow velocity profile to interpret hydrimorphological features of China s Yangtze Three-Gorges valley. Chin Sci Bull 50(7) 679-684... 

Fig. 11.2. Schematic representation of the primary structure of secreted AChE B of N. brasiliensis in comparison with that of Torpedo californica, for which the three-dimensional structure has been resolved. The residues in the catalytic triad (Ser-His-Glu) are depicted with an asterisk, and the position of cysteine residues and the predicted intramolecular disulphide bonding pattern common to cholinesterases is indicated. An insertion of 17 amino acids relative to the Torpedo sequence, which would predict a novel loop at the molecular surface, is marked with a black box. The 14 aromatic residues lining the active-site gorge of the Torpedo enzyme are illustrated. Identical residues in the nematode enzyme are indicated in plain text, conservative substitutions are boxed, and non-conservative substitutions are circled. The amino acid sequence of AChE C is 90% identical to AChE B, and differs only in the features illustrated in that Thr-70 is substituted by Ser.

Ripoll, D.R., Faerman, C.H., Axelson, P.H., Silman, I. and Sussman, J.L. (1993) An electrostatic mechanism for substrate guidance down the aromatic gorge of acetylcholinesterase. Proceedings of the National Academy of Sciences USA 90, 5128-5132. 

---