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Gold colloids coating with proteins

Colloidal gold A suspension (or colloid) of submicrometer-sized particles of gold in a fluid, usually water. A colloidal gold conjugate consists of gold particles coated with a selected protein or macromolecule, such as an antibody, protein A or protein G. Because of their high electron density, the gold particles are visible in the electron microscope without further treatment. [Pg.143]

Tolsen, N. D., Boothroyd, B., and Hopkins, C. R. (1981) Cell-surface labelling with gold colloidal particles, the use of avidin and staphylococcal protein A-coated gold in conjunction with biotin and Fc-beanng ligands. J. Microsc 123,215—226. [Pg.282]

Colloidal gold probes are widely used in the biological sciences for both light and electron microscopy. A gold probe is in electron dense sphere of gold coated with an immunologically active protein. There are two aspects to be considered when making the probe. [Pg.163]

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Colloid coatings

Colloidal gold

Colloidal gold protein

Gold coatings

Protein colloid

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