Glycyl-L-valine

TABLE 18.10. Enthalpies of Dilution and Initial and Einal Molalities for Aqueous Solutions of Glycyl-L-Valine at 298.15 K... 

This type of interaction has now been used to prepare a variety of imprinted polymers where A-toluoyl-glycyl-L-valine methyl ester acted as chiral template and 3-trifluoroacetylamino-5-(4-styryl)pyrazole 23f as the binding site monomer. In batch rebinding experiments, some of them showed a pronounced enantioselectivity towards rebinding of template (up to a = 2.7). The re-uptake of substrate to the polymers was generally only low. 

To overcome this problem, the amidopyrazol binding site has been combined with a guanidinium group. This binding site shows a high association constant in acetonitrile with, e.g., 7V-toluoyl-glycyl-L-valine as shown in Fig. 7 [63]. 

Glycyl-L-valine (CyHj 03N2) (Values in Vol.l, p.298 and Vol.5, p.93) 80SKc,83Ab,84YM, 85PO... 

Schroeder, Iacobellis, and Smith,148 who set out to determine whether or not further evidence might be gleaned for the observation134 that water prevents the deleterious effect of autoclaving on the nutritive value of dried skim-milk. The amino acids used in this study were glycine, L-leucine, and DL-valine glycyl-L-leucine and glycyl-DL-valine were the peptides chosen. 

Mitani and Inoue (49) found that the inhibition of mycelial growth of P. sasakii by polyoxins was protected by glycyl-L-alanine, glycyl-D,L-valine and D,L-alanylglycine. Therefore, the peptides may act as antagonists to the incorporation of polyoxins into the cell of the fungus. 

Fig. II, Allowed areas of the steric map for various dipeptides. In area 0 no conformations are allowed. Conformations in areas 1 to 4 are allowed for glycyl glycine, in areas 2 to 4 for glycyl-L-alanine, in areas 3 to 4 for higher straight-chain homologs, while only area 4 is allowed for glyeyl-L-valine and glycyl -n -isoleucine. The circles marked R and L indicate the location of the standard right- and left-handed a-helix on the steric map (Nemethy etal., 1900a,b).

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