Glycosylation of Immunoglobulins Produced in Plants

The first comparative study of a mammalian glycoprotein produced in a transgenic plant system was performed by Cabanes-Macheteau et al. (1999). Guy s 13 antibody, which is specific for a cell-surface protein of 

Biopharmaceuticals in Plants Toward the Next Century of Medicine 

In another study, Ko et al. (2003) expressed human antirabies MAb in transgenic tobacco plants and compared its A-glycosylation patterns 

In addition to antibodies, numerous human blood glycoproteins have been produced in transgeiuc plants. Most are indistinguishable from their mammalian counterparts in terms of amino acid sequence, conformation, and biological activity. However, structural differences can be observed with 

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