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Glycosylated prodrug

A. Namane, C. Gouyette, M. P. Fillion, G. Fillion, T. Huynh-Dinh, Improved Brain Delivery of AZT Using a Glycosyl Phosphotriester Prodrug ,./. Med. Chem. 1992, 35, 3039-3044. [Pg.602]

Ubiquitous glycosylated carboxylesterases (CarbE, EC 3.1.1.1), formerly named ali-esterases, are B-esterases belonging to the multigene enzyme superfamily of a/P hydrolases (Hosokawa and Satoh, 2006 Satoh and Hosokawa, 2006). In principle this class of isozymes plays a major role in pharmacokinetics by hydrolytic biotransformation of exogenous ester-drugs and ester-prodrugs. However, their physiological fimction still remains unclear (Satoh and Hosokawa, 2006). [Pg.768]

Sampathkumar, S.-G., Jones, M. B., Meledeo, M. A., et al. (2006). Targeting glycosylation pathways and the cell cycle sugar-dependent activity of butyrate-carbohydrate cancer prodrugs. Chem. Biol., 13, 1265-1275. [Pg.216]


See other pages where Glycosylated prodrug is mentioned: [Pg.161]    [Pg.179]    [Pg.215]    [Pg.161]    [Pg.179]    [Pg.215]    [Pg.576]    [Pg.200]    [Pg.123]    [Pg.98]    [Pg.221]    [Pg.524]    [Pg.1784]    [Pg.415]    [Pg.194]    [Pg.200]    [Pg.1277]    [Pg.177]    [Pg.253]    [Pg.200]    [Pg.279]    [Pg.99]    [Pg.235]    [Pg.274]    [Pg.831]    [Pg.235]   
See also in sourсe #XX -- [ Pg.21 , Pg.161 ]

See also in sourсe #XX -- [ Pg.161 ]




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