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Glycosphingolipids active

Glycosphingolipids are constituents of the outer leaflet of plasma membranes and are important in cell adhesion and cell recognition. Some are antigens, eg, ABO blood group substances. Certain gangliosides function as receptors for bacterial toxins (eg, for cholera toxin, which subsequently activates adenylyl cyclase). [Pg.202]

Lochnit, G., Dennis, R.D., Ulmer, A.J. and Geyer, R. (1998a) Structural elucidation and monkine-inducing activity of two biologically active zwitterionic glycosphingolipids derived from the porcine parasitic nematode Ascaris suum. Journal of Biological Chemistry 273, 466-474. [Pg.312]

The concept of the catabolism of glycosphingolipids by glycohydro-lases has entered a new era with the discovery of protein activators, but there are many questions remaining to be answered. What is the physiological role of the activators What is the mode of their action ... [Pg.284]

Although glycosphingolipids are the specific lipid components in the antigen-antibody complex, their activity is markedly enhanced by other (auxiliary) lipids such as lecithin and lecithin-cholesterol mixtures (15). The present study deals with the effect of lipid composition on the penetration of lactoside—cholesterol and lactoside—lecithin monolayers by rabbit y-globulin. We also investigated the lecithin-cholesterol system. Furthemore, since criteria for the existence of lipid-lipid complexes in monolayers are still few (8, 17), we have used infrared spectroscopy to examine lipid mixtures for the presence of complexes. [Pg.165]

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See also in sourсe #XX -- [ Pg.55 , Pg.56 , Pg.57 , Pg.58 , Pg.59 , Pg.60 , Pg.61 , Pg.62 ]



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