Glycopeptides interacting

Table 2-2. The relative strength of potential interactions between glycopeptide CSPs and chiral analytes.

This relatively new class of CSPs incorporates glycopeptides attached covalently to silica gel. These CSPs can be used in the normal phase, reversed phase, and polar organic modes in LC [62]. Various functional groups on the macrocyclic antibiotic molecule provide opportunities for tt-tt complexation, hydrogen bonding, and steric interactions between the analyte and the chiral selector. Association of the analyte... 

The complex oligosaccharides comprising the Y and T antennae of three glycoproteins have been studied by c.d. spectroscopy. Five antennae were studied in all, because two of the proteins have two closely related forms. The c.d. for the three fundamental oligosaccharides are given in Fig. 36. These are asparagine-linked glycopeptides, and the intense, conservative c.d. band that results from the interaction between the two amides has already been discussed in Section III,2. Fig. 36 shows that the c.d. spectra... 

Figure 14.7 Models of phosphorylated high-mannose M7 and a glycopeptide mimic obtained by MD calculation showing similar conformations. They are seen from the point of interaction with the mannose-6-phosphate receptor. Disaccharide phosphates are emphasized as spheres.76...

If a certain analyte contains more than one polar functional groups capable of interacting with the glycopeptide-containing CSP and at least one of these groups is near the... 

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