Glycolipids function

W. Curatolo, Glycolipid Function , Biochim. Biophys. Acta, 906, 137 (1987)... 

Glycoconjugate, 991 Glycogen, function of, 1001 structure of, 1001 Glycol, 234, 662 Glycolic acid, pKa of, 756 structure of, 753 Glycolipid, 991... 

The characterization of the first functional cyanobacterial PPTase from Nodularia spumigena SORXQ was reported and its ability to modify carrier proteins from heterocyst glycolipid synthesis and nodularin toxin synthesis was demonstrated. This now opens the door to harness the biotechnological potential of cyanobacterial natural products formation. 

Guo CX, Boullanger P, Liu T, Jiang L. Size effect of polydiacetylene vesicles functionalized with glycolipids on their colorimetric detection ability. J Phys Chem B Condens Matter Mater Surf Interfaces Biophys 2005 109 18765-18771. 

Su YL, Li JR, Jiang L, Cao J. Biosensor signal amphfication of vesicles functionalized with glycolipid for colorimetric detection of Escherichia coli. J Colloid Interface Sci 2005 284 114-119. 

The structure and function of cell membranes have long been associated with lyotropic liquid crystalline phases. Since most of the glycolipids are amphitropic (both thermotropic and lyotropic) their was an increase of interest in the comparison of the structures of both types of mesophases formed by the same compound. 

Alkyl (or acyl) derivatives of the 6-amino-6-deoxy carbohydrates are examples of derivatives in which the hydrophilic and hydrophobic moieties are linked at other positions than C-1. Thus 6-amino-6-deoxy-D-galactose derivatives 34 were prepared from l,2 3,4-di-0-isopropylidene-6-0-tosyl-a-D-galacto-pyranose by the following reactions (1) substitution of the leaving group at C-6 by a phthaloyl function, (2) hydrazinolysis to afford a 6-amino-6-deoxy intermediate, (3) reaction of acyl or sulfonyl chlorides at the amino function, (4) deprotection of the acetal rings to afford the expected glycolipid 34 [56]. 

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