Transaminase, glutamic-oxalacetic

For example, glutamic-oxalacetic transaminase activity can be standardized with oxalacetate but not with "convenient" substances such as pyruvate (J ). When reference serums are used, the label value should be confirmed at frequent intervals by the actual method being used routinely, as label values can be in error (19). Conversion factors to convert the results obtained by one method into those obtained by another can give erroneous results and should not be used. 

Schneider, A. J. Willis, H. J. Sources of variation in a standardized and semi-micro procedure for serum glutamic oxalacetic transaminase. Clin. Chem. (1958), 4, 392-408. Atwood, J. G. DiCesare, J. L. Making enzymatic methods optimum for measuring compounds with a kinetic analyzer. Clin. Chem. (1975), n, 1263-1269. 

Amador, E. and sod, M. F. Characterization of the normal serum glutamic-oxalacetic transaminase activity of healthy adults. Am. J. Clin. Path. (1967), 47,... 

Increases glutamic oxalacetate transaminase activity in Daphnia... 

Dose-dependent decrease in serum glutamate oxalacetate transaminase (GOT) activity in 96 h, but values overlapped normal GOT range from this hatchery 50... 

Glutamate oxalacetic transaminase (SGOT), now frequently referred to as aspartate aminotransferase (AST)... 

GGT, y-glutamyl transpeptidase GOT, glutamic-oxalacetic transaminase GPT, glutamic-pyruvic transaminase. 

Sabath, L. D., Gerstein, D. A., and Finland, M., Serum glutamic oxalacetic transaminase. False elevations during administration of erythromycin. New Engl. J. Med. 279, 1137-1139 (1968). 

The results for rats fed browned or control egg albumin are also listed in Table V. The only significant change evident was a depressed serum glutamic-oxalacetic transaminase activity in the browned fed rats after six months. 

Changes in glucose-6-phosphatase, forminoglutamic acid transferase, urocanase, formylase, methyl-H4-folate dehydrogenase, histidiase, glutamic oxalacetic transaminase and carbonyl transferase and ornithine... 

Urinary excretions of nicotinic acid metabolites and 2-pyridone, as well as of 4-pyridoxic and xanthurenic acids were determined in 15 South African Bantu pellagrins before and after tryptophan administration (P13). Red blood cell riboflavine levels and serum glutamic-oxalacetic transaminase levels were also measured. The authors discussed the apparent inability of the pellagra patients to convert tryptophan to nicotinic acid as indicated by their low excretion of nicotinic acid metabolites before and after tryptophan load. The possibility that the subjects were also suffering from a riboflavine deficiency was also discussed. 

C14. Cope, F. W., and Polis, B. D., Increased plasma glutamic oxalacetic transaminase activity in monkeys due to non-speeifie stress efEect. J. Aviation Med. 30, 90 (1959). 

K4. Karmen, A., A note on the spectrophotometric assay of glutamic-oxalacetic transaminase in human blood serum. ]. Clin. Invest. 34, 131 (1955). 

Kll. Kove, S., Goldstein, S., and Wroblewski, F., Activity of glutamic-oxalacetic transaminase in the serum in the neonatal period. Pediatrics 20, 584 (1957). 

M18. Murphy, E. G., and Cherniak, M. M., Glutamic oxalacetic transaminase activity in the serum in muscular dystrophy and other neuromuscular disorders in childhood. Pediatrics 22, 1110 (1958). 

P4. Pearson, C. M., Serum enzymes in muscular dystrophy and certain other muscular and neuromuscular diseases. I. Serum glutamic oxalacetic transaminase. New Engl. ]. Med. 256, 1069 (19.57). 

Siekert, R. G., and Fleisher, G. A., Serum glutamic oxalacetic transaminase in certain neurologic and neuromuscular diseases. Proc. Staff Meetings Mayo Clin. 31, 459 (1956). 

Glutamic-oxalacetate transaminase (GOT) is released into the blood stream as a result of myocardial infarction. The enzyme is assayed in serum by following the decrease in the absorbance of NADH in the malic dehydrogenase (MDH)-coupled reaction sequence shown below. 

Chang, E.S. (1978). Strip test for the quantitative determination of glutamic oxalacetic transaminase in serum. Clin. Chem. 24,1037, Abstr. 245. 

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