Glucoside, preparation

Bollenback, Methyl Glucoside, Preparation, Physical Constants, Derivatives , Academic Press, NY (1958) 4) Merck (1968), 687-L... 

Add 10.5 mL of agarose (kept in the 50-56°C water bath) to 200 mg of a-methyl-D-glucoside prepared in another tube heated in the water bath. Then add the antiserum and carefully mix the tube contents see Notes 4 and 6). 

Emil Fischer, as part of a study of a series of S- and iV-glucosides, prepared 1-D-glucosylurea and 1-D-glucosylthiourea from the corresponding isocyanate (IV) and isothiocyanate (V), respectively. These intermediates were obtained by the condensation of tetra-O-acetyl-a-D-glucopyranosyl bromide (III) with silver cyanate or thiocyanate in anhydrous xylene. The... 

Among the most important C-disaccharide syntheses reported in 1989 is the preparation of C-sucrose. This analog of table sugar is interesting in that unlike natural sucrose, it cannot be metabolized to lower sugars. An actual synthesis of C-sucrose was reported by Nicotra, et ai.,22>23 and is illustrated in Scheme 8.7.5. As shown, the C-glucoside, prepared as discussed in Chapter 2, was converted to a metallated alcohol in 97% yield. Subsequent oxidation of the metal with iodine followed by oxidation of the alcohol to a ketone and... 

Octyl glucoside preparative SEC Bio-Rad Bio-Beads SM-2,6 g pH 8 aqueous buffer Analysis of fractions 283 ... 

U8 C, (-l-)-or (-)- m.p. 133X. Occurs combined in the glucoside amygdalin. Prepared by hydrolysis of mandelonitrile (ben-zaldehyde cyanohydrin). It is administered in large doses in the treatment of urinary infections. 

C7H6O2 Oily liquid of aromatic odour b.p. 196°C. (t is prepared by the action of chloroform and caustic potash on phenol (the Reimer-Tiemann reaction) or by the oxidation of the glucoside salicin. It is easily reduced to salicyl alcohol or oxidized to salicylic acid. 

The following preparation works excellently if it is carried out in a laboratory which has become inoculated by the methylglucoside from previous preparations, or alternatively if some of the glucoside is available for "seeding the solution of the crude material otherwise there may be a considerable delay before crystallisation starts. 

Among the well-known Solanum species that have been chemically examined are S. nigrum, S. tuberosum (potato) and S. lycopersicum (tomato). From these and other species an alkaloidal glucoside, which was first prepared by Desfosses, has been obtained. This substance has been named solan ine, but it is not certain that all the plants recorded as containing solanine contain the same solanine or that the alkaloid has been obtained in a pure state in each case. 

It was first artificially prepared by Tiemann from the glucoside coni-ferin, which occurs in the cambium of various coniferous woods. The constitution of vanUlin is that of methyl protocatechuic aldehyde—... 

It was of interest to determine whether glycosides of 6-deoxy-D-xylo-hex-5-enopyranose were susceptible to enzyme hydrolysis by / -glucosi-dase. Since aromatic glucosides are hydrolyzed by this enzyme at a much faster rate than aliphatic glycosides, phenyl 6-deoxy-/ -D-rt/Zo-hex-5-enopyranoside (18) was prepared (20). Phenyl / -D-glucopyranoside was converted to the 6-tosylate by selective esterification and then, by conventional procedures, transformed to phenyl 2,3,4-tri-0-acetyl-6-deoxy-... 

FIGURE 3 Effect of the amount of cholesterol on the particle size. Phosphatidylcholine/cholesterol liposomes were prepared by the octyl glucoside dilution technique. The begin concentration of the mixed micelles was 150 mM octyl glucoside and 10 mM phosphatidylcholine in 10 mM tris(hydroxymethyl)aminomethane and 0.9% NaCl, pH 7.4. Dilution was performed with an automatic titration unit at a dilution rate (= dilution factor, relative to the initial volume, per unit of time) of 0.026 sec"l ( a and ) or 0.69 sec l ( and o). Mean diameters after dilution and ) and after filtration ( L and q) are repi sented. (Adapted from Jiskoot et al, 1986a.)... 

It is to be noticed that although the anhydro ring of levoglucosan is stable to alkali (Tanret s preparative method consisted in the heating of aromatic jS-D-glucosides with aqueous alkali), it readily undergoes scission in the presence of acid. An isomeric glucose anhydride prepared in 1912 by E. Fischer showed, however, very different properties. 

---