Glucose with acetic acid

Saccharic acid. Use the filtrate A) from the above oxidation of lactose or, alternatively, employ the product obtained by evaporating 10 g. of glucose with 100 ml. of nitric acid, sp. gr. 1 15, until a syrupy residue remains and then dissolving in 30 ml. of water. Exactly neutralise at the boiling point with a concentrated solution of potassium carbonate, acidify with acetic acid, and concentrate again to a thick syrup. Upon the addition of 50 per cent, acetic acid, acid potassium saccharate sepa rates out. Filter at the pump and recrystaUise from a small quantity of hot water to remove the attendant oxahc acid. It is necessary to isolate the saccharic acid as the acid potassium salt since the acid is very soluble in water. The purity may be confirmed by conversion into the silver salt (Section 111,103) and determination of the silver content by ignition. 

Incidental reactions that have been reported include the preparation of derivatives of 5-(hydroxymethyl)-2-furaldehyde by reaction of D-fructose in acetic or propionic acid in the presence of the respective anhydride.158 The condensation of D-glucose with phenol has been effected in acetic acid in the presence of dry hydrogen chloride, prior to resinification,157 and the reaction of sucrose with thionyl chloride in acetic acid-acetic anhydride produced partially acetylated chlorodeoxysucroses.158 Sucrose has been condensed with maleic anhydride in acetic anhydride mixed with acetic acid or formic acid, to give solid products having an undetermined structure.159... 

Derivation Reacting cellulose (wood pulp or cotton linters) with acetic acid or acetic anhydride, with H2S04 catalyst. The cellulose is fully acetylated (three acetate groups per glucose unit), and at the same time the sulfuric acid causes appreciable degradation of the cellulose polymer so that the product contains only 200-300 glucose units per polymer chain. At this point in the process the cellulose acetate ordinarily is partially hydrolyzed by the addition... 

Finally, Section 8.5 discusses the design of chromatographic reactors, using as examples the esterification of P-phenethyl alcohol with acetic acid and the isomerization of glucose. 

The coefficient for the water molecule acting as a proton donor (that is, as an acid catalyst) may be calculated from equation 12 by using data for the mutarotation of D-glucose at 18°, with acetic acid as the reference point. From equation 15,... 

D-arabino-Hexose ( n-glucose ) phenylosazone Ar,AT -diphenylformazan (7), obtained by coupling diazotized aniline with n-glucose phenylosazone (1), is converted to the osotriazole formazan (8) on boiling it for a few minutes with acetic acid. ... 

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