Glucose sugar oxidation reaction

Phillips (P2) has studied the radiation reactions of sugars in dilute solution and reported a preferential oxidation occurring at the C 6 position, which results in conversion of the glucose to glucuronic acid. Other oxidizing reactions resulting in the formation of aldehyde offer alternative pathways. 

FIGURE 16.9 Oxidation of a sugar to a lactone. An example of an oxidation reaction of sugars oxidation of a-D-glucose hemiacetal to give a lactone. Deposition of free silver as a silver mirror indicates that the reaction has taken place. 

What are the oxidative reactions of the pentose phosphate pathway The pentose phosphate pathway is an alternative pathway for glucose metabolism. In this pathway five-carbon sugars, including ribose, are produced from glucose. In the oxidative reactions of the pathway, NADPH is also produced. 

The direct incomplete oxidation of sugars without phosphorylation leads to the formation of the corresponding ketones. The aldoses are oxidized into aldonic acids. The aldehydic function of this sugar is transformed into a carboxylic acid function. Glucose is oxidized into gluconic acid in this manner. The glucose oxidase catalyzes the reaction, which is coupled with the reduction of FAD. In acetic acid bacteria, electrons and protons are transported by the cytochrome chain to oxygen, which is the final acceptor. 

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