Glucose, identification

Dyer DG, Blackledge JA, Thorpe SR and Baynes JW (1991b) Formation of pento-sidine during nonenzymatic browning of proteins by glucose identification of glucose and other carbohydrates as possible precursors of pentosidine in vivo. J Biol Ghem 266,11654-11660. 

H. Lerche, M. Pischetsrieder, and T. Severin, Maillard reaction of D-glucose identification of a colored product with conjugated pyrrole and furanone rings, J. Agric. Food Chem., 2002, 50, 2984-2986. 

Methionine Glucose Identification and flux analysis through of a novel pathway for isoleucine biosynthesis [40]... 

Ribose and a-glucose are monosaccharides that occur in nature. The carbon atoms are numbered for identification purposes. 

The identification of non-peptidic lead structures remains a challenge. Screening of natural product extracts led to the identification of two po-lyhydroxylated biphenyls ((10a) and (10b), Figure 2.13) that show submicromolar inhibition of the viral protease [156]. A recent report discloses polyesters of glucose (11) and gallic acid (12) as micromolar inhibitors of the NS3 protease [157]. 

H8. Hirono, A., Kuhl, W., Gelbart, T., Forman, L., Fairbanks, V. F., and Beutler, E., Identification of the binding domain for NADP of human glucose-6-phosphate dehydrogenase by sequence analysis of mutants. Proc. Natl. Acad. Sci. U.S.A. 86,10015-10017 (1989). 

H15. Hirono, A., Fujii, H and Miwa, S Identification of two novel deletion mutations in glucose-... 

V12. Vives Corrons, J. L. 1., Rovira, A., Pujades, A., Vulliamy, T., and Luzzatto, L., Molecular heterogeneity of glucose-6-phosphate dehydrogenase (G6PD) in Spain and identification of two new base substitutions in the G6PD gene, Blood 84 (Suppl. 1), 551a (1994). 

LC ESI MS allows also the identification of other anthraquinones in madder preparations. Based on structural information obtained by NI mass spectra and specific retention times (signals corresponding to quasi-molecular ions [M—H] and fragment ions [M—C02—H] ), pseudopurpurin (peaks at m/z 299.1 and 255.3) and munjistin (at m/z 283.1 and 239.3) are found in the natural material. Alizarin glycoside is identified by deprotonated quasi-molecular ions at m/z 401.1 and ions formed by the loss of glucose at m/z 239.1. Similar ions are found to be characteristic of lucidin... 

Fractionation of mycobacteria resulted in the identification of two cellular immunostimulatory components, namely TDM and MDPs. Both are normally found in association with the mycobacterial cell wall. TDM is composed of a molecule of trehalose (a disaccharide consisting of two molecules of a-D-glucose linked via an a 1-1 glycosidic bond), linked to two molecules of my-colic acid (a long-chain aliphatic hydrocarbon-based acid) found almost exclusively in association with mycobacteria. TDM, although retaining its adjuvanticity, is relatively non-toxic. 

---