Glucose homeostasis fasted

Gatifloxacin was well tolerated in patients with non-insu-lin-dependent diabetes mellitus maintained with diet and exercise (432). It had no significant effect on glucose homeostasis, beta cell function, or long-term fasting serum glucose concentrations, but it caused a brief increase in serum insulin concentrations. 

Figure 32-4. Phases of glucose homeostasis in a normal human during a prolonged fast. Adapted from Ruderman et al. (1975).

This new category is analogous to IGT, but is diagnosed by a fasting glucose value between that of normal and diabetic individuals. It is a metabolic stage between normal glucose homeostasis and diabetes. As with IGT, persons with IFG are at increased risk for the development of diabetes and cardiovascular disease. IFG and IGT are not clinical entities, but rather risk factors for diabetes and cardiovascular disease. 

Glucose homeostasis in the fasting state. TG, Triacylglycerol RBC, red blood cells FA, fatty acid AA, amino acid. 

Some inborn errors of metabolism present with hypoglycemia, occurring after periods of extended fasting. Disorders of reduced tolerance to fasting include glucose homeostasis... 

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