Glucose growth hormone excess

An excess of insulin can cause hypoglycaemia and the hormones that respond to this condition to restore normal glucose levels are known as the counter-regulatory hormones. They are adrenaline, glucagon, growth hormone and cortisol. An increase in the blood levels of these hormones can sometimes be used to conhrm a diagnosis of hypoglycaemia. 

EXCESS results in a normally proportioned giant when overproduction occurs in childhood. Overproduction in an adult results tn acromegaly. Such individuals have abnormally proportioned growth features, especially enlarged hands, feet and jaw. There may be hyperglycemia, as growth hormone is also involved in glucose metabolism. 

The reasons for changes in glucose metabolism are not understood. Many mechanisms have been considered including changes in cortisol secretion, alterations in tissue glucose utilisation, production of excessive amounts of growth hormone, and alterations in liver function. ... 

The condition which results from excess growth hormone secretion in adults, the usual cause being a pituitary adenoma. The condition is characterized by increases in bulk of the bones and soft tissues, especially of the jaw, hands and feet. Because growth hormone is involved in glucose homeostasis, impaired glucose tolerance can occur. Acromegaly can be diagnosed biochemically by ... 

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