Glasses safe storage temperature

As regards the role played by excipients in determining the glass transitions of the freeze-concentrate and the final dried product, they may increase Tg, thus allowing the implementation of shorter cycles by raising the maximum safe temperature for ice sublimation. In addition, any excipient that increases Tg of the final dried product will thereby raise the product s maximum safe storage temperature. This is of particular importance for the production of shelf-stable products. Some excipients, particularly those of a PHC type, also stabilise proteins in... 

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