Ginkgol

Satyan KS, Jaiswal AK, Ghosal S, Bhattacharya SK. (1998). Anxiolytic activity of ginkgolic acid conjugates from Indian Ginkgo biloba. Psychopharmacology (Berlin). 136(2) 148-52. 

Allergic reactions are a significant concern with unprocessed ginkgo leaf (ginkgolic acid) but are much less... 

Figure 1 Structures of (A) ginkgolide A, ginkgolide B, bilobalide, (B) flavonolgly-cosides (R=H kaempferol-3-O-rutinoside R=OH quercetin-3-O-rutinoside R=0CH3 isorhamnetin-3-O-rutinoside) and (C) ginkgolic acids (R=Ci3H27, C15H31, C15H29, C15H33).

Hausen BM. The sensitizing capacity of ginkgolic acids in guinea pigs. Am J Contact Derm 1998 9 146-148. 

EGb761 is made up of 24% flavonoid glycosides and 6% terpenes, which are accepted as active prindples. Many undesirable constituents of Ginkgo biloba leaves (e.g., ginkgolic add due to its allergic action) are eliminated by the extraction procedures used to prepare the extract... 

Ginkgolic acids Ginkgo biloba (Ginkgoaceae) Quasi-apoptotic (cytotoxic but... 

Fuzzati N, Pace R, Villa F. A simple HPLC-UV method for the assay of ginkgolic acid in ginkgo biliba extract. Fitoterapia 2003 74 247-256. 

Alkylphenols with long alkyl groups have been identified from many plants [91]. Anacardic acids (Ginkgolic acids) are the most intensively... 

The isomer of Fig (2)-2, anacardic acid 8(E)-monoene has been synthesised by a Xrans elimination reaction as depicted in Scheme 2 [234], which also depicts the route used for the (Z)- isomer, ginkgolic acid. [235],... 

Anacardic 8(Z)-monoene (ginkgolic acid) has been synthesised from... 

Apart from cardanol (Fig. 1-1,2,4, and 5) which collectively is a minor natural component in Anacardium occidentale, the first 3-substituted monohydric phenols isolated were, ginkgol (identical with cardanol monene), (depicted in Fig. 1-2), from Ginkgo biloba, and camnospermanol, (Fig. 1-6), from Camnospermum auriculata. More recently a number of 4-substituted monohydric phenols, (depicted in Fig.l), have been obtained from natural sources including, elenic acid, R-2,4-dimethyl-22-(4-hydroxyphenyl)-docos-3(E)-enoic acid, 7, navenone,... 

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