Genotoxicity, organophosphates

Genotoxicity of Organophosphate Ester Hydraulic Fluids In Vitro... [Pg.12]

Organophosphate Ester Hydraulic Fluids. No studies were located regarding genotoxic effects in humans or animals after inhalation exposure to organophosphate ester hydraulic fluids. Genotoxicity studies for organophosphate ester hydraulic fluids are discussed in Section 2.5. [Pg.67]

Other genotoxicity studies for organophosphate ester hydraulic fluids are discussed in Section 2.5. [Pg.130]

No results indicating genotoxicity were observed in in vitro studies that examined six organophosphate ester hydraulic fluids for gene mutation, deoxyribonucleic acid (DNA) damage, or chromosomal aberrations in eukaryotes (see summarized data in Table 2-11). [Pg.219]

Identifying biochemical markers. These are typically sublethal biological responses to chemical pollution which are not immediately apparent. For example, genotoxic carcinogens can cause measurable DNA adduct formation, while neurotoxins, such as organophosphate pesticides, can cause reductions of cholinesterase levels in invertebrates. [Pg.107]